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Fig. 4 | Genome Medicine

Fig. 4

From: Race-specific coregulatory and transcriptomic profiles associated with DNA methylation and androgen receptor in prostate cancer

Fig. 4

Race comparisons reveal distinct gene enrichments that correlate with progression-free survival. Left panels represent differentially expressed genes utilizing DESeq2, middle panels represent gene set enrichment analysis based on clusterProfiler, and right panels represent hazard ratios based on calculated GSVA scores. A Comparison of all prostate tumors from AA and EA men. B Race-specific comparisons show distinct pathways in prostate tumors of AA and EA men younger than 55. C Comparisons show distinct pathways in prostate tumors of AA men younger than 55 compared to AA men ≥ 55. NES: Normalized Enrichment Score. An asterisk indicates a significant (p < 0.05) enrichment of the indicated pathway

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Genome Medicine

ISSN: 1756-994X

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