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Fig. 1 | Genome Medicine

Fig. 1

From: Race-specific coregulatory and transcriptomic profiles associated with DNA methylation and androgen receptor in prostate cancer

Fig. 1

Differentially methylated regions between prostate tumors from AA and EA men reveal race-specific enrichment of pathways and transcript factors. A and B Manhattan plots representing differentially methylated regions in prostate tumors from AA (A) and EA men (B) across all chromosome locations. HyperDMRs are in the top half, represented as −log[10]FDR and hypoDMRs are in the bottom half, represented as log[10]FDR. C and D Enriched pathways associated with DMRs in prostate tumors from AA (C) and EA (D) men. E and F Lisa-derived enrichment of epigenetic regulators enriched in prostate tumors from AA (E) and EA men (F). X-axis: represents hypermethylated regions in prostate tumors, and Y-axis: represents hypomethylated regions in prostate tumors

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Genome Medicine

ISSN: 1756-994X

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