Fig. 2

Characterization of DNA methylation signatures in cancers. A Proportion of each cancer type in which different DNA methylation signatures are present. B Cosine similarity between different methylation signatures (MSs). C Cosine Similarity and Spearman correlation between the probe weight of methylation signatures derived from cancer cell lines (CC-MSs) and tumor tissues (TCGA-MSs). The top 20 weighted probes in each signature are labeled with the corresponding gene names.