Fig. 4

Potential extrinsic immune response landscapes in the high-risk and low-risk groups. A Volcano plots of 29 immune signatures in the high-risk and low-risk groups. Immune signatures enriched in cancer tissues are marked in red; immune signatures enriched in normal tissues are marked in blue. B Correlations among 29 immune signatures in the high-risk (top right panel) and low-risk (low left panel) groups. C Comparison of the correlation coefficient among 29 immune signatures between the high-risk and low-risk groups. Correlation coefficients greater than 0.7 were included in the analysis. D Gene set enrichment analysis of the high-risk and low-risk groups. E Comparison of the CYT score between the high-risk and low-risk groups. F Comparison of fibroblast abundances between the high-risk and low-risk groups. G Comparison of the expression patterns of chemokines between the high-risk and low-risk groups. H After normalizing the data according to the immune cell fraction, the expression patterns of chemokines were compared between the high-risk and low-risk groups