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Fig. 1 | Genome Medicine

Fig. 1

From: Genome-wide identification and characterization of circular RNA m6A modification in pancreatic cancer

Fig. 1

The framework of Circm6A. The pipeline of Circm6A consists of two steps: first, identification of circRNAs from MeRIP-seq IP and INPUT samples according to PCC and PEM signals; second, identification of circRNAs and linear transcripts with m6A modifications by examining whether the circRNAs or regions in linear transcripts are significantly enriched in IP samples compared to INPUT samples in the MeRIP-seq data. PCC, paired chiastic clipping signals; PEM, paired-end mapping signals

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