Fig. 2

Evaluation of cancer cell lines. a General classification heatmap of CCLs extracted from CCLE. Column annotations of the heatmap represent the labeled cancer category of the CCLs given by CCLE and the row names of the heatmap represent different cancer categories. b Bar plot represents the proportions of each classification category in CCLs across cancer types ordered from the cancer types with the highest proportion of correct and correct mixed CCLs to lowest proportion. CCLs’ general classification profiles are categorized into 4 categories: correct (red), correct mixed (pink), no classification (light green), and other classification (dark green) based on the decision threshold of 0.25. c Comparison between SKCM general CCN scores from bulk RNA-seq classifier and SKCM malignant CCN scores from scRNA-seq classifier for SKCM CCLs. d Comparison between SARC general CCN scores from bulk RNA-seq classifier and CAF CCN scores from scRNA-seq classifier for SKCM CCLs. e Comparison between GBM general CCN scores from bulk RNA-seq classifier and GBM neoplastic CCN scores from scRNA-seq classifier for GBM CCLs. f Comparison between SARC general CCN scores and CAF CCN scores from scRNA-seq classifier for GBM CCLs. The green dotted lines indicate the decision threshold for scRNA-seq classifier and general classifier