Protein* | Pos. | Ref. Allele | Alt. Allele | Alt. Allele Freq. | Dominant Alt. Allele Freq. (150090) | Europe (88266) | Asia (7818) | NAm (38203) | SAm (1702) | AFR (1211) | OCE (12837) | UK (68017)** |
---|---|---|---|---|---|---|---|---|---|---|---|---|
S | 614 | D | V:G:S:N | 1:131490:2:10 | 0.877 | 0.975 | 0.940 | 0.866 | 0.890 | 0.866 | 0.868 | 0.883 |
nsp12 | 314 | N | H:F:L:S | 2:114:131053:1 | 0.876 | 0.973 | 0.938 | 0.863 | 0.887 | 0.876 | 0.865 | 0.881 |
N | 203 | R | G:K:M:I:S | 9:57773:73:1:37 | 0.388 | 0.426 | 0.394 | 0.374 | 0.316 | 0.393 | 0.440 | 0.380 |
N | 204 | G | R:V:L:Q:T | 57,327:5:319:4:1 | 0.385 | 0.424 | 0.393 | 0.373 | 0.312 | 0.392 | 0.439 | 0.379 |
orf3a | 57 | Q | K:Y:R:H:L | 1:6:6:35047:2 | 0.234 | 0.267 | 0.227 | 0.236 | 0.210 | 0.193 | 0.199 | 0.248 |
nsp2 | 85 | T | V:I | 1:25913 | 0.173 | 0.195 | 0.156 | 0.180 | 0.160 | 0.090 | 0.153 | 0.180 |
nsp6 | 37 | L | F | 11,992 | 0.080 | 0.087 | 0.112 | 0.079 | 0.061 | 0.082 | 0.073 | 0.079 |
nsp2 | 120 | I | V:F:M | 7:11996:1 | 0.080 | 0.094 | 0.061 | 0.082 | 0.059 | 0.054 | 0.059 | 0.083 |
S | 222 | A | T:V:P:I:S:F | 4:11819:2:1:12:1 | 0.079 | 0.099 | 0.148 | 0.057 | 0.177 | 0.135 | 0.026 | 0.085 |
orf10 | 30 | V | A:I:L | 2:2:11619 | 0.078 | 0.097 | 0.146 | 0.056 | 0.176 | 0.132 | 0.025 | 0.084 |
N | 220 | A | V:T | 11,555:5 | 0.077 | 0.097 | 0.146 | 0.056 | 0.176 | 0.131 | 0.025 | 0.083 |
S | 477 | S | T:R:G:I:N:K | 1:19:2:59:9811:1 | 0.067 | 0.077 | 0.044 | 0.070 | 0.048 | 0.045 | 0.043 | 0.068 |
N | 194 | S | A:L:P:T | 30:6441:2:1 | 0.043 | 0.052 | 0.043 | 0.035 | 0.031 | 0.053 | 0.038 | 0.049 |
orf8 | 84 | L | F:C:S:V | 1:1:6338:1 | 0.042 | 0.046 | 0.053 | 0.043 | 0.049 | 0.040 | 0.048 | 0.042 |
orf8 | 24 | S | L | 6151 | 0.041 | 0.053 | 0.033 | 0.036 | 0.034 | 0.009 | 0.022 | 0.048 |
S | 18 | L | F:I | 5888:1 | 0.040 | 0.048 | 0.071 | 0.030 | 0.106 | 0.059 | 0.017 | 0.041 |
nsp5 | 15 | G | S:D | 5433:5 | 0.036 | 0.039 | 0.035 | 0.036 | 0.022 | 0.038 | 0.044 | 0.036 |
orf3a | 251 | G | V:S:D:C | 5252:31:4:6 | 0.035 | 0.035 | 0.063 | 0.037 | 0.031 | 0.040 | 0.034 | 0.030 |
nsp13 | 541 | Y | C | 2606 | 0.017 | 0.019 | 0.032 | 0.017 | 0.018 | 0.021 | 0.019 | 0.017 |
nsp13 | 504 | P | L:H:S | 2535:1:111 | 0.017 | 0.020 | 0.032 | 0.017 | 0.018 | 0.022 | 0.021 | 0.017 |