Table 1 The breakdown of typed vs imputed SNPs per PRS score
From: Genotype imputation and variability in polygenic risk score estimation
| Â | Number of SNP | Reference | |||
|---|---|---|---|---|---|
Total | Found | Typed | Imputed | ||
Coronary artery disease (CAD) | |||||
 PRSCAD | 163 | 161 | 38 | 123 | [27] |
 metaGRSCAD | 1,745,180 | 1,736,608 | 143,724 | 1,592,884 | [31] |
 GPSCAD | 6,630,150 | 6,238,460 | 567,297 | 5,671,163 | [3] |
Type 2 diabetes (T2D) | |||||
 PRS-GWAST2D (547) | 558 | 547 | 66 | 481 | [32] |
 PRS-GWAST2D (397) | 403 | 397 | 29 | 368 | [33] |
 PRS-GWAST2D (170487) | 171,249 | 170,487 | 10,152 | 160,335 | [33] |
 GPST2D | 6,917,436 | 6,482,889 | 570,779 | 5,912,110 | [3] |
Breast cancer (BC) | |||||
 PRS-GWASBC (239) | 313 | 239 | 34 | 205 | [34] |
 PRS-GWASBC (2935) | 3820 | 2941 | 325 | 2616 | [34] |
 GPSBC | 5218 | 4457 | 374 | 4083 | [3] |
Atrial fibrillation (Afib) | |||||
 PRS-GWASAfib | 166 | 166 | 19 | 147 | [35] |
 GPSAfib | 6,730,541 | 6,302,924 | 570,913 | 5,732,011 | [3] |
Alzheimer’s disease (AD) | |||||
 PRS-GWASAD | 29 | 29 | 2 | 27 | [36] |
Glaucoma | |||||
 PRS-GWASGlaucoma | 2673 | 2657 | 224 | 2433 | [37] |