Skip to main content
Fig. 2 | Genome Medicine

Fig. 2

From: Distinct patterns of complex rearrangements and a mutational signature of microhomeology are frequently observed in PLP1 copy number gain structural variants

Fig. 2

An overview of genomic rearrangements as seen on aCGH in 50 individuals with PMD. Genomic rearrangements at Xq22 vary in size and genomic positions. The largest duplication (~ 4.5 Mb) is found in individual BAB8954. Three individuals show additional duplications distant from the duplicated PLP1 locus (individuals BAB8920, BAB8923, and BAB8934). The black numbers refer to genomic coordinates on chromosome X. The left column lists the 50 subjects studied. Slash lines indicate a break in numbering for genomic coordinates. The location of PLP1 is indicated by a black vertical broken line

Back to article page

Genome Medicine

ISSN: 1756-994X

Contact us