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Fig. 6 | Genome Medicine

Fig. 6

From: A modular transcriptome map of mature B cell lymphomas

Fig. 6

Characterization of lymphoma pattern types (PATs). a For each lymphoma patient, the PAT, clinical characteristics, previous molecular classifications, genomic characteristics and immunohistochemical (IHC) phenotypes are indicated in the barplots. Thresholds for classification of IHC markers are described in [17]. b Mapping of cases showing selected characteristics into the correlation network. It shows, e.g. that different previous classifications of lymphomas, such as ABC and GCB-DLBCL, accumulate in different areas of the network, which, in turn, associate with certain PATs. c Percentage of selected leukocyte cells according to their mRNA signatures across the PATs. ‘No PAT’ samples were assigned as ‘∅’ and distributed into PAT groups using a minimum Euclidian distance between sample and mean group portraits

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