Skip to main content
Fig. 4 | Genome Medicine

Fig. 4

From: A modular transcriptome map of mature B cell lymphomas

Fig. 4

Expression portraits of B cells and lymphomas, and their relation with respect to the GC biology. See also Additional file 1: Figure S3 for the full gallery of group-related expression portraits. Activated spot combinations are given as letters in the portraits. The particular spot patterns observed for the different lymphoma subtypes can be related to their functional context and associated key genes (compare with Fig. 2). For example, DZ-related types such as BL are proliferative as indicated by upregulation of spot D, which is on a lower expression level in LZ-related DLBCL. ABC-DLBCL and MM activate spot H, which is, in turn, virtually inactive in BL, GCB-DLBCL and FL

Back to article page