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Fig. 2 | Genome Medicine

Fig. 2

From: Cross-genetic determination of maternal and neonatal immune mediators during pregnancy

Fig. 2

Linkage disequilibrium regional genomic plot of fetal genome-wide associated SNPs with maternal serum levels of sIL2R-α and 11 neonatal immune mediators. a Fetal rs75885714 on chromosome 3p24.3 associated with CCL17 (β = −0.53, SE = 0.05, P = 8.6 × 10−21); b The independent fetal SNP rs12496141 which maps in the PLCL2 gene and (c) Fetal rs12327057 on chromosome 18p11 associated with sIL2R-α maternal levels (β = − 0.42, SE = 0.07, P = 1.4 × 10−8) maps to a lincRNA ADCYAP1 gene. The x-axis represents the genomic position; the y-axis shows the negative logarithm of the observed association P value for each tested SNP. Plotted with LocusZoom tool [42]

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