Human genetic variants and age are the strongest predictors of humoral immune responses to common pathogens and vaccines

Table 3 Significant associations of rare variants collapsed per gene set with IgA levels

Phenotype	Chromosome	Gene	P value	Q	No. of rare markers	No. of Common Markers
IgA levels	2	ACADL	3.42 × 10⁻¹¹	18.09	5	2
IgA levels	2	TMEM131	7.83 × 10⁻¹¹	17.89	13	2

ISSN: 1756-994X