Fig. 5
From: Single-cell transcriptome analysis of lineage diversity in high-grade glioma
a Hierarchical clustering of the correlation between each transformed subpopulation and a database of cell type-specific expression profiles with high variability across the data set. We find three cell type clusters referred to as Neural/ESC, Immune, and Mesenchymal/MSC which divide the tumor cell subpopulations into three major groups. b Gene ontology analysis of the differentially expressed genes between the group III tumors (PJ017/PJ032) and the remaining tumors (PJ016, PJ018, PJ025, PJ030, PJ035, PJ048) after removal of genes specific to the untransformed immune cells in PJ017 and PJ032. The group III tumors show a clear immunological gene signature that is specific to the transformed cells