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Fig. 4 | Genome Medicine

Fig. 4

From: Disease-specific regulation of gene expression in a comparative analysis of juvenile idiopathic arthritis and inflammatory bowel disease

Fig. 4

Transcriptional risk scores associate with disease status. a IBD-TRS scores within disease sub-types for 39 genes associated with IBD in [58]. Gene expression values for each selected gene were transformed into z-scores, polarized relative to risk according to whether the eQTL activity of the risk allele discovered by GWAS increases or decreases transcript abundance, and summed to generate the TRS as in [60]. b New RA-TRS based on 23 genes associated with RA by GWAS [59]

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