Skip to main content
Fig. 1 | Genome Medicine

Fig. 1

From: Population-based analysis of ocular Chlamydia trachomatis in trachoma-endemic West African communities identifies genomic markers of disease severity

Fig. 1

Composite in vivo conjunctival disease severity phenotype in ocular Chlamydia trachomatis infection. A composite in vivo phenotype was derived using principal component analysis (PCA) for dimension reduction of two phenotypic traits: a disease severity score (using the P score value) and C. trachomatis load (where C. trachomatis load was log transformed and cut-offs determined from the resulting density plot (see Additional file 1: Figure S1)). Each circle represents an individual infection (represented on the x-axis (Index), n = 81). Circle size reflects C. trachomatis load and circle colour reflects inflammatory P score (P0–P3) defined using the modified FPC (follicles, papillary hypertrophy, conjunctival scarring) grading system for trachoma [39]

Back to article page