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Fig. 1 | Genome Medicine

Fig. 1

From: Detection and analysis of methicillin-resistant human-adapted sequence type 398 allows insight into community-associated methicillin-resistant Staphylococcus aureus evolution

Fig. 1

Phylogeny of ST398 isolates. We aligned 174 ST398 genome sequences (77 from our study, 88 from that by Price et al. [14], and 9 additional published sequences [12, 27,28,29,30]) and one ST36 sequence (outgroup). The phylogeny was inferred by MrBayes v3.2.1 [20], and time estimation was performed with the BEAST v1.8.0 program [22]. Isolate characteristics are shown on the right, including presence of SCCmec type and ST398 origin-defining genes. 1–7, seven ST398 CA-MRSA isolates from this study; X, Y, two ST398 isolates of Chinese origin from the Price et al. study [14] that our analysis determined as CA-MRSA of human ancestry rather than transferred LA-MRSA strains. We also analyzed the presence of SNPs associated with the human and animal clades (branches 1–4, marked in blue) and listed the corresponding SNPs in comparison to the human clade in Additional file 1: Table S1

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