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Table 1 Variants in the linkage region after filtering

From: Linkage, whole genome sequence, and biological data implicate variants in RAB10 in Alzheimer’s disease resilience

SNP

Chromosome

Position

Gene

Variant type

MAF (controls/cases)

MAF (1000 Genomes/ExAC

rs142787485

2

26358156

RAB10

3′ UTR

0.041/0.028

0.0152/NA

rs77747916

2

29405333

CLIP4

3′ UTR

0.0099/0.0069

0.0087/NA

rs41291171

2

33623713

LTBP1

3′ UTR

0.049/0.049

0.0243/NA

rs7653

10

71910316

SAR1A

3′ UTR

0.03/0.0092

0.0175/NA

rs143318821

10

102105884

SCD

Promoter

NA

0.004/NA

rs41562219

10

103340081

POLL

Exonic p.D337D; ncRNA p.D429D

0.0075/0.0080

0.0029/0.0034

chr10:103347900

10

103347900

POLL; DPCD

Promoter; 5′UTR

0.0012/0

NA/NA

rs116928523

10

103912209

NOLC1

Exonic p.L14L

0.0075/0.0057

0.003/0.006

  1. For each variant, the dbSNP identifier (SNP), chromosome, position, closest gene(s) (Gene), variant type, minor allele frequency (MAF) in controls and cases, and frequency from the 1000 Genomes Project and Exome Aggregation Consortium (ExAC) are provided (NA if not present in the database)