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Table 1 Percentage frequencies of the most common copy number events in LGD, HGD and SCC samples

From: The genomic road to invasion—examining the similarities and differences in the genomes of associated oral pre-cancer and cancer samples

 

LGD

HGD

SCC

P value

3p loss

28.95

72.46

0.72

0.3994

4p loss

13.16

44.93

0.33

0.9453

5q loss

23.68

69.57

0.56

0.9787

9p loss

26.32

65.22

0.50

0.7044

11 pq loss

18.42

50.72

0.36

0.7893

18q loss

7.89

42.03

0.50

0.0646

3q gain

36.84

68.12

0.60

0.2041

5p gain

39.47

62.32

0.51

0.0428

7 pq gain

39.47

47.83

0.50

0.0067

8q gain

50.00

57.97

0.59

0.0009

12p gain

7.89

31.88

0.36

0.2404

Expected

12

38

30

 
  1. The p values that each event differs from the expected frequencies were calculated from the overall fraction of genome altered and total sample number for each group using a chi-squared test. As 11 regions were tested, p values below 0.0045 are considered significant
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Genome Medicine

ISSN: 1756-994X

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