Fig. 3

Alternative splicing transcript variants. Different types of alternative splicing can give rise to transcripts that are functionally distinct from a nominal reference model. Red represents the untranslated region (UTR) and green represents the coding sequence (CDS). The retained intron is illustrated as non-coding as a retained intron is presumed to represent an immature transcript. Some transcripts can contain exons that are mutually exclusive (boxed). All the types of alternative exon splicing events shown here can also occur in non-coding genes. There can also be multiple alternative poly(A) features within the gene models, as seen for the skipped-exon transcript