Table 1 Subject characteristics for the RNA-seq dataset

Sex

3 M/3 F

3 M/3 F

3 M/3 F

3 M/3 F

-

Age, years

48–63

41–56

50–63

46–63

0.155

BMI, kg/m²

24.0 ± 0.6^b,d

35.2 ± 3.6^a,c

24.4 ± 2.7^b,d

33.2 ± 2.8^a,c

2.04e-07

Fasting glucose (0 h), mmol/l

5.4 ± 0.6^c

5.7 ± 0.5

9.0 ± 3.8^a

8.1 ± 1.4

0.0156

Glucose (2 h), mmol/l

5.2 ± 1.0^c,d

5.5 ± 1.2^c,d

18.0 ± 7.3^a,b

16.4 ± 3.5^a,b

1.12e-05

Insulin (0 h), pmol/l

25 ± 7^d

60 ± 33

38 ± 35

79 ± 43^a

0.0438

Insulin (2 h), pmol/l

175 ± 123

197 ± 153

281 ± 303

509 ± 376

0.137

HOMA-IR

0.47 ± 0.13^d

1.13 ± 0.61

0.81 ± 0.72

1.61 ± 0.83^a

0.0347

Cholesterol (total), mmol/l

5.2 ± 0.8

4.9 ± 0.3

5.1 ± 0.7

5.0 ± 0.6

0.918

Cholesterol (HDL), mmol/l

1.7 ± 0.5

1.3 ± 0.3

1.4 ± 0.4

1.2 ± 0.3

0.202

Cholesterol (LDL), mmol/l

2.8 ± 0.5^d

3.4 ± 0.6

3.1 ± 0.4

3.6 ± 0.5^a

0.0512

Triglycerides, mmol/l

1.0 ± 0.2

1.2 ± 0.8

1.7 ± 0.8

2.1 ± 0.7

0.0586

Free fatty acids (0 h), mmol/l

0.31 ± 0.09^c,d

0.44 ± 0.13

0.56 ± 0.22^a

0.61 ± 0.07^a

0.0078

Free fatty acids (2 h), mmol/l

0.07 ± 0.03

0.07 ± 0.04

0.13 ± 0.05

0.13 ± 0.03

0.0182