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Fig. 4 | Genome Medicine

Fig. 4

From: Intersect-then-combine approach: improving the performance of somatic variant calling in whole exome sequencing data using multiple aligners and callers

Fig. 4

Performance of the intersect-then-combine (ITC) approach. Sensitivity (a) and FPR/Mb (b) in identifying somatic SNVs after applying the ITC strategy compared with performance using each single alignment pipeline in combination with each mutation caller. Sensitivity (c) and FPR/Mb (d) in identifying somatic indels after applying the ITC strategy compared with performance using each single alignment pipeline in combination with each mutation caller

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