Fig. 4From: Intersect-then-combine approach: improving the performance of somatic variant calling in whole exome sequencing data using multiple aligners and callersPerformance of the intersect-then-combine (ITC) approach. Sensitivity (a) and FPR/Mb (b) in identifying somatic SNVs after applying the ITC strategy compared with performance using each single alignment pipeline in combination with each mutation caller. Sensitivity (c) and FPR/Mb (d) in identifying somatic indels after applying the ITC strategy compared with performance using each single alignment pipeline in combination with each mutation callerBack to article page