Fig. 3From: Intersect-then-combine approach: improving the performance of somatic variant calling in whole exome sequencing data using multiple aligners and callersEffect of parameter adjustments on sensitivity and FPR. Changes in sensitivity (a, c) and FPR/Mb (b, d) after optimised filtering of Mutect2 (a, b) or Strelka (c, d) calls in combination with the two alignment pipelines (BWA/GATK and Novocraft)Back to article page