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Table 2 Multivariable regression analyses of potential clinical factors associated with the intra-patient temporal instability of the oral and stool microbiomes of AML patients

From: Characterization of oral and gut microbiome temporal variability in hospitalized cancer patients

 

P value

Variables

Oral SDI CV

Oral UUCV

Oral WUCV

Stool SDI CV

Stool UUCV

Stool WUCV

Age

0.287

0.864

0.529

0.425

0.779

0.885

Received piperacillin/tazobactam >72 h

0.475

0.208

0.175

0.507

0.215

0.973

Received cefepime >72 h

0.108

0.557

0.943

0.508

0.669

0.639

Received carbapenem >72 h

0.748

0.762

0.832

0.360

0.482

0.681

Days on all antibioticsa

0.031b

0.0001b

0.002b

0.392

0.858

0.580

Days on treatment antibiotics

0.205

0.060

0.163

0.917

0.633

0.451

Number of antibiotics received

0.089

0.380

0.874

0.357

0.724

0.167

Non-fludarabine high intensity chemotherapy

0.723

0.581

0.935

0.415

0.605

0.456

Hypomethylator-based chemotherapy

0.734

0.712

0.181

0.244

0.900

0.612

  1. a Includes prophylactic antibiotics
  2. b Significant P values
  3. UUCV unweighted UniFrac coefficient of variation, WUCV weighted UniFrac coefficient of variation