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Fig. 4 | Genome Medicine

Fig. 4

From: Microbiomic differences in tumor and paired-normal tissue in head and neck squamous cell carcinomas

Fig. 4

Relative abundances of differentially represented taxa stratified by T-stage. Box plots representing relative abundances of phylum Actinobacteria (top), genus Actinomyces (middle), and genus Parvimonas (bottom) stratified by T-stage. Dark horizontal lines represent the median, with the box representing the first (Q1) and third (Q3) quartiles, and the outer fences 1.5 × interquartile range. Outliers are not plotted. a Samples stratified by type (normal = blue, tumor = orange), with darker colors representing higher T-stage. In both normal and tumor samples, the relative abundances of Actinobacteria and Actinomyces decrease, while Parvimonas increases, with increasing T-stage. b Samples stratified by location (oral cavity/oropharynx = magenta, hypopharynx/larynx = green), with darker colors representing higher T-stage. In the oral cavity/oropharynx, the relative abundances of Actinobacteria and Actinomyces decrease, while Parvimonas increases, with increasing T-stage. In hypopharyngeal/laryngeal samples, only Actinobacteria is decreased with increasing T-stage

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