Referencesa
| Populationb
| Casesc (n) | Controlsd (n) | Effect allelee
| Effect allele frequencyf
| OR (95% CI)g
|
P valueh
|
---|
[15] | Caucasian | 1200 | 2270 | C | 0.209 | 1.12 (1.15–1.29) | 1.26 × 10–3
|
[14] | Chinese | 1012 | 1362 | C | 0.322 | 1.15 (1.07–1.30) | 2.6 × 10–2
|
[12, 13] | Chinese | 324 | 486 | C | 0.36 | 1.29 (1.10–1.45) | 4 × 10–6
|
 | Combined | 2536 | 4118 |  |  |  |
1.14 × 10
–6
|
-
aInitial study describing the cohorts used for association
-
bEthnicity of the population under study
-
cNumber of atopic dermatitis cases
-
dNumber of controls
-
eAllele used for the calculating the odds ratio statistics
-
fAllele frequency of the effect allele in the individual study population
-
gOdds ratio estimated with 95% confidence interval
-
h
P value estimated for the case control association study for atopic dermatitis phenotype in the individual study population
- Meta P value is the P value calculated for all three cohorts combined using the Stoufier’s z trend meta-analysis which considers individual study P value sample sizes and effect directions using Meta P program [20]