Fig. 8

Comparative enrichment analysis for cis-eQTL SNPs under four immunologically relevant conditions. The four eQTL SNP sets are: naive state (Naïve cis-eQTLs), induced by 2-h LPS (LPS2 cis-eQTLs), by 24-h LPS (LPS24 cis-eQTLs), and by 24-h IFN-γ (IFN24 cis-eQTLs). All analyses are using the disease subgraph of EFO and respecting the ontology tree. a Side-by-side bar plots comparing the significant EFO terms across the four conditions. The horizontal dotted lines separate terms shared by four conditions (top), by three conditions (upper middle), by two conditions (lower middle), and unique to one condition (bottom). b DAG plot comparing the significant EFO terms across the four conditions. Nodes/terms are coloured according to the number of conditions sharing the terms