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Fig. 2 | Genome Medicine

Fig. 2

From: Non-coding single nucleotide variants affecting estrogen receptor binding and activity

Fig. 2

The location of rs62022087 in genome and ER ChIP-binding sites. a Schematic view of DSV genomic position in IGF1R gene. b The position of IGF1R SNP with regards to canonical ERE sequence. Binding score was calculated by Jaspar database tool (http://jaspar.genereg.net). c The distribution of ER ChIP-seq reads flanking rs62022087 SNP in different cell line models as well as patient tumors [1]. The numbers in parentheses are the fraction and percentage of the reads containing mutant allele, respectively

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