Fig. 1

Major advances in omics-related fields. This figure highlights landmark studies providing key insights into parasite makeup, development, and pathogenesis (yellow boxes) as well as crucial technical advances (blue boxes) since the first Plasmodium genomes were published in 2002 [2, 5, 12, 13, 27, 29, 31, 39, 40, 42, 43, 48–50, 53, 54, 57, 66, 114, 115, 151, 153–178]. AID auxin-inducible degron, ART artemisinin, cKD conditional knockdown, CRISPR clustered regularly interspaced short palindromic repeats, DD destabilization domain, K13 kelch13, Pb P. berghei, Pf P. falciparum, TSS transcription start site, TF transcription factor, ZNF zinc finger nuclease