Microbiota-based model improves the sensitivity of fecal immunochemical test for detecting colonic lesions

Table 1 Sensitivities and specificities for FIT and MMT. The 95 % confidence intervals were computed with 2000 stratified bootstrap replicates

Diagnosis		Fecal immunochemical test		Multitarget microbiota test
		True positives	Sensitivity (95 % CI)	True positives	Sensitivity (95 % CI)
Cancer	n = 120	90	75.0 (67.5–82.5)	110	91.7 (86.7–95.8)
Adenoma	n = 198	31	15.7 (10.6–20.7)	90	45.5 (38.4–52.5)
Any lesions	n = 318	121	38.1 (32.7–43.4)	200	62.9 (57.2–67.9)
		True negatives	Specificity (95 % CI)	True negatives	Specificity (95 % CI)
Normal	n = 172	167	97.1 (94.2–99.4)	155	90.1 (85.5–94.2)

ISSN: 1756-994X