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Fig. 2 | Genome Medicine

Fig. 2

From: CoINcIDE: A framework for discovery of patient subtypes across multiple datasets

Fig. 2

True positive rates (TPR) and true negative rates (TNR) of simulations. TPR plotted against FPR for the first six CoINcIDE logged gene expression simulation scenarios for varied minimum mean similarity thresholds. The FPR is truncated at 0.02 because no FPR values ever reached above this threshold. a-f were produced using the set standard deviation random normal noise level of 0.8 (Additional file 3: Figure S5A-G plot in detail each simulation scenario at more noise levels.) a The results for the high quality simulation scenario with an equal cluster size and equal number of clusters, (b) results for the random cluster size and equal number of clusters, (c) results for the equal cluster size and random number of clusters with a minimum of two clusters per dataset, (d) results for the equal cluster size and random number of clusters with a minimum of one cluster per dataset, (e) results for the random cluster size and random number of clusters per dataset with a minimum of two clusters per dataset, and (f) results for the random cluster size and random number of clusters per dataset with a minimum of one cluster per dataset scenario. The seventh simulation is not shown here due to space constraints but plots for this simulation scenario for equal cluster size but 50 % random/noisy clusters can be found in Additional file 3: Figures S5G and S6G

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