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Table 2 Variant summary data for chr16q12.2 classified by functional region and BMI status

From: Complete re-sequencing of a 2Mb topological domain encompassing the FTO/IRXB genes identifies a novel obesity-associated region upstream of IRX5

Region

Size of region (kb)

Number of variant locations

Variant locations per Kb

Mean MAF

Average number variants per individual

Average number non-ref alleles per individual

CNEs

25.1

Cases 117

4.66

0.118

20.03

27.52

Controls 109

4.34

0.127

19.94

27.60

Total 141

5.61

0.098

19.98

27.57

Coding

17.2

Cases 38

2.21

0.075

4.61

5.37

Controls 56

3.26

0.051

4.75

5.40

Total 70

4.07

0.041

4.69

5.39

Non-coding

1,957.7

Cases 11014

5.51

0.181

2853

3916

Controls 11826

5.91

0.167

2836

3892

Total 13980

6.94

0.142

2843

3902