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Fig. 3 | Genome Medicine

Fig. 3

From: Complete re-sequencing of a 2Mb topological domain encompassing the FTO/IRXB genes identifies a novel obesity-associated region upstream of IRX5

Fig. 3

Association of SNPs in cases vs. controls. Minus log10(P value) of Case/Control association for each SNP across the 2 Mb interval generated from Haploview [38] and represented by vertical blue lines. The first peak (at 53.82 Mb) in the intron of FTO shows the known association at rs9939609:T > A and reflects the strong linkage disequilibrium across that region. The second peak (54.84 Mb) indicates a novel associated region upstream of IRX5

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