Fig. 2

Comorbidity within autism and ID/DD. The frequency of comorbid features within (a) all cases with autism (n = 5,872), boys (n = 4,588) and girls (n = 1,284) with autism, and within (b) all individuals with ID/DD (n = 28,553), boys (n = 17,061) and girls (n = 11,492) with ID/DD is shown. The frequency of comorbid features within (c) girls (F) and boys (M) is shown for a representative set of genomic disorders. Additional file 1: Table S8 shows data for all CNVs with sample sizes >10. Due to a limited sample size within the genomic disorder cohort, only ID/DD can be shown. Samples sizes for the CNVs are: 1q21.1 del: M = 30, F = 21; 15q13.3 del: M = 25, F = 20; 16p11.2 del: M = 45, F = 29; 16p12.1 del: M = 20, F = 9; 16p13.11 del: M = 25, F = 26; 1q21.1 dup: M = 27, F = 20; 15q11.2q13.1 dup (Prader-Willi region dup): M = 26, F = 21; 16p11.2 dup: M = 29, F = 16; 16p13.11 dup: M = 25, F = 26; 22q11.2 del (DiGeorge Syndrome): M = 35, F = 30; Smith Magenis Syndrome (SMS): M = 10, F = 13; 22q13 del: M = 11, F = 34