Skip to main content

Table 3 Beliefs about Alzheimer’s disease and genetic testing within each recruitment cohort among participants who completed the pre-education questionnaire

From: Associations between self-referral and health behavior responses to genetic risk information

 

Actively recruited (n = 163)

Self-referred (n = 444)

  

Continuous/ordinal measures (range)

Mean ± SD

Mean ± SD

∆ (95% CI)

P

  Perceived susceptibility, second trial (0–100)

51.5 ± 22.1

58.6 ± 20.8

7.1 (1.7 to 12.6)

0.011

  Perceived susceptibility, third trial (0–100)

35.5 ± 25.3

34.0 ± 21.3

−1.5 (1.7 to 12.6)

0.664

  Perceived seriousness (1–5)

3.1 ± 1.5

3.2 ± 1.5

0.1 (−0.2 to 0.4)

0.389

  AD concern (1–5)

3.4 ± 0.8

3.5 ± 0.7

0.1 (0.0 to 0.2)

0.122

  AD attentiveness (1–4)

1.9 ± 0.8

2.1 ± 0.8

0.2 (0.1 to 0.4)

0.006

  Coping self-efficacy (0–100)

86.3 ± 19.4

86.0 ± 18.7

−0.3 (−3.9 to 3.2)

0.861

  Perceived pros (1–5)

3.5 ± 0.8

3.5 ± 0.7

0.0 (−0.1 to 0.1)

0.949

  Perceived cons (1–5)

1.9 ± 0.7

1.9 ± 0.7

−0.1 (−0.2 to 0.0)

0.228

  Causal belief: genetics/heredity (1–5)

4.1 ± 0.9

4.1 ± 0.9

0.0 (−0.2 to 0.1)

0.785

  Causal belief: lifestyle (1–5)

3.5 ± 1.2

3.4 ± 1.1

−0.1 (−0.3 to 0.1)

0.525

Binary measures

n (%)

n (%)

OR (95% CI)

P

  Interest in genetic risk assessment

159 (97%)

434 (98%)

1.2 (0.4 to 3.4)

0.779

  Expectation of reassurance

19 (12%)

65 (15%)

1.3 (0.7 to 2.3)

0.412

  Expectation of aided decision making

21 (13%)

58 (13%)

1.0 (0.6 to 1.8)

0.940

  1. Results are adjusted for demographic factors that varied by cohort (age, race, income, employment status, study site, and study trial). CI, confidence interval; OR, odds ratio.