Figure 6
From: Assessment of patient-derived tumour xenografts (PDXs) as a discovery tool for cancer epigenomics
Enrichment of (epi)genomic regions with changing methylation status after xenografting. Each probe on the 450 K array is annotated to a genomic (TSS1500, Body, 3′ UTR…) and epigenomic (island, shore, shelf, none) region. These were combined for each probe to form a unique (epi)genomic annotation and enrichments were calculated using a random resampling strategy. IGR, intergenic region; TSS, transcription start site.