Figure 1From: Assessment of patient-derived tumour xenografts (PDXs) as a discovery tool for cancer epigenomicsOsteosarcoma PDX derivation scheme. A single fragment from each patient tumour, approximately 1 mm in diameter, was inserted subcutaneously into each flank of a SCID mouse. Patient tumour 1 (T1P) gave rise to three first generation PDXs and two second generation PDXs, while patient tumour 2 (T2P) was used to produce one PDX at each generation.Back to article page