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Table 1 Clinical and demographic information for the analysis population

From: An integrated transcriptome and expressed variant analysis of sepsis survival and death

Clinical variable

SIRS

Sepsis survivors

Sepsis non-survivors

n

23

78

28

Age (years)

64.9 ± 14.4

56.1 ± 18.0

67.6 ± 17.0

Gender (% Male)

34.8%

59.0%

60.7%

Race (B/W/O)

16/6/1

47/26/5

21/6/1

APACHE II

16.8 ± 7.7

14.7 ± 6.6

21.3 ± 7.1

Pathogena

   

S. aureus

N/A

20 (26%)

5 (18%)

S. pneumoniae

N/A

20 (26%)

4 (14%)

Enterobacteriaceae

N/A

23 (29%)

3 (11%)

Total leukocyte countb

11.2 (8.8, 13.5)

14.6 (9.7, 18.7)

15.1 (10.4, 21.9)

% Neutrophils

77.0 (73.5, 83.3)

85.0 (82.0, 91.0)

87.4 (82.0, 92.8)

% Lymphocytes

13.0 (7.6, 15.8)

7.0 (4.0, 11.0)

8.0 (4.2, 11.8)

% Monocytes

7.1 (4.4, 9.8)

5.0 (3.0, 8.0)

4.5 (2.0, 6.0)

Co-morbidities

   

Alcohol abuse

17.4%

17.9%

10.7%

Neoplastic disease

13.0%

6.4%

21.4%

Diabetes

30.4%

32.1%

35.7%

Congestive heart failure

0%

6.4%

14.3%

Chronic kidney disease

26.1%

21.8%

25.0%

Chronic liver disease

8.7%

5.1%

21.4%

Immunosuppression

0%

6.4%

7.1%

Smoker

21.7%

30.8%

25.0%

  1. Data presented as mean ± standard deviation. aOther identified pathogens include: Candida albicans, Clostridium difficile, Coagulase-negative Staphylococcus, Enterococcus species, Legionella, Listeria monocytogenes, Mycoplasma pneumoniae, Pseudomonas aeruginosa, Streptococcus non-pneumoniae (agalactiae, pyogenes, viridans group). No significant differences in pathogen frequency were identified between Sepsis Survivors and Sepsis Non-survivors using Fisher’s exact test. Subjects were counted more than once in cases of polymicrobial infection.
  2. bReported as cells x 109/liter, median (1st quartile, 3rd quartile). Leukocyte differential percentages exclude one SIRS subject, nine Sepsis Survivors, and two Sepsis Deaths for whom differential data were not available.
  3. B/W/O: black/white/other; N/A: not applicable.