Table 1 Partial AUC performance and random permutation P value for three metrics using 152 filtered compound profiles
From: Systematic evaluation of connectivity map for disease indications
Method | FPR = 0.01 (Specificity = 0.99) | FPR = 0.1 (Specificity = 0.9) | |||
|---|---|---|---|---|---|
Fold enrichment | OneAUC0.01 | Fold enrichment | OneAUC0.1 | AvgAUC0.1 | |
KS | 0.7 | 3.17e-5 (P = 0.94) | 0.9 | 0.005 (P = 0.81) | 0.003 (P = 0.90) |
XSum | 3.8 | 2.17e-4 ( P = 0.0035) | 1.4 | 0.0086 ( P = 0.014) | 0.011 ( P = 0.035) |
XCos | 2.3 | 1.82e-4 (P = 0.056) | 1.2 | 0.006 (P = 0.16) | 0.006 (P = 0.37) |