SRST2: Rapid genomic surveillance for public health and hospital microbiology labs

Table 3 Comparison of SRST2 and ResFinder (ref 19) for detection of acquired resistance genes

Correct calls	N (%)
Aac(60)-Iaa (chromosomally encoded core gene, expect in all strains)
Both methods	35 (83%)
SRST2 only	7 (17%)
ResFinder only	0
Acquired resistance genes (total 44 detected)
Both methods	24 (55%)
SRST2 only	20 (45%)
ResFinder only	0

42?S. enterica serovar Typhimurium read sets (accessions in Table 1) with >1 mean read depth were analysed using the ResFinder website, and also with SRST2 using the sequence database downloaded from the ResFinder website. Results are shown separately for the chromosomally encoded core resistance gene aac(60)-Iaa, which is expected to be in all strains, and horizontally acquired resistance genes.

ISSN: 1756-994X