Table 2 Genomic locations and other details of 31 single nucleotide variants (SNVs) detected in the genomes of isolates from the Acinetobacter baumannii pulsotype 27 outbreak in Birmingham, UK, 2011 to 2013
SNV no. | Location in reference assembly | Orthologue annotation | Amino acid | Codon (residue in bold) | Orthologue | ||
|---|---|---|---|---|---|---|---|
| Â | Â | Â | Original | New | Original | New | Â |
1 | 2354692 | Two-component sensor kinase transcription regulator protein PmrB | Pro | Leu | CCA | CTA | AB57_3172 |
2 | 1696968 | Diguanylate cyclase | Lys | STOP | AAA | TAA | AB57_0627 |
3 | 219628 | 16S rRNA methyltransferase GidB | Arg | Ser | CGT | AGT | AB57_1794 |
4 | 2953356 | 3-oxoacyl-ACP reductase | Leu | Trp | TTG | TGG | AB57_0871 |
5 | 2354857 | Two-component sensor kinase transcription regulator protein PmrB | Thr | Ile | ACT | ATT | AB57_3172 |
6 | 164435 | Adenylate/guanylate cyclase | Asp | Gly | GAC | GGC | AB57_1850 |
7 | 164513 | Adenylate/guanylate cyclase | Tyr | Phe | TAT | TTT | AB57_1850 |
8 | 2354642 | Two-component sensor kinase transcription regulator protein PmrB | Thr | Pro | ACC | CCC | AB57_3172 |
9 | 2568699 | Threonine synthase | Leu | Leu | TTA | CTA | AB57_0327 |
10 | 555356 | Catalase/peroxidase HPI | Leu | Ile | TTA | ATA | AB57_0488 |
11 | 2961444 | AraC family transcriptional regulator | Val | Val | GTC | GTT | AB57_1179 |
12 | 48566 | LysR family transcriptional regulator | Leu | Ile | CTC | ATC | AB57_1964 |
13 | 1778342 | Lysine/ornithine N-monooxygenase BasC | Trp | STOP | TGG | TAG | A1S_2384 |
14 | 1600195 | Bifunctional cyclohexadienyl dehydrogenase/ 3-phosphoshikimate 1-carboxyvinyltransferase | Gly | Ser | GGT | AGT | AB57_2630 |
15 | 3658279 | Non-coding | Intergenic 88 bp from start of serB | Â | Â | Â | |
16 | 2448345 | Plasmid replicase protein | His | Tyr | CAC | TAC | ACINIS123_A0022 |
17 | 706757 | Putative transport protein | Ala | Thr | GCT | ACT | ABAYE2100 |
18 | 3286974 | ABC transporter ATP-binding protein | Gly | Cys | GGT | TGT | ABAYE2100 |
19 | 2501364 | Regulatory helix-turn-helix protein, lysR family protein | Val | Ile | GTA | ATA | ABBFA_001413 |
20 | 2354659 | Two-component sensor kinase transcription regulator protein PmrB | Arg | Leu | CGC | CTC | AB57_3172 |
21 | 2720233 | Non-coding | intergenic 72 bp from start of kdsD | Â | Â | Â | |
22 | 3818799 | Argininosuccinate synthase | Val | Val | GTT | GTA | AB57_1152 |
23 | 727482 | Oxidoreductase short-chain dehydrogenase/reductase family | Leu | Leu | CTA | CTT | AB57_2417 |
24 | 2153319 | Diguanylate cyclase/phosphodiesterase | Tyr | Asn | TAC | AAC | AB57_2291 |
25 | 2879522 | Glutathionylspermidine synthase | Asp | Glu | GAT | GAG | HMPREF0022_00853 |
26 | 2055876 | D-ala-D-ala-carboxypeptidase, penicillin-binding protein | Thr | Lys | ACG | AAG | AB57_2923 |
27 | 2698063 | D-and L-methionine ABC transporter ATP-binding protein MetN | Arg | Trp | CGG | TGG | AB57_1716 |
28 | 1499950 | Peptidase M20D, amidohydrolase | Glu | Gly | GAA | GGA | AB57_2996 |
29 | 396513 | Non-coding | intergenic 80 bp from start of TetR/AcrR transcriptional regulators | Â | Â | Â | |
30 | 2371782 | Hypothetical protein | Val | Ala | GTT | GCT | ACIN5074_3260 |
31 | 1935255 | Hypothetical protein | Arg | His | CGT | CAT | AB57_1009 |