Networking of differentially expressed genes in human cancer cells resistant to methotrexate

Table 4 Genes differentially expressed in common among breast cancer cell lines resistant to MTX

GenBank	Gene name	Description	Ratio MCF7	Ratio MDA-MB-468
NM_019093	UGT1A1/3/4/5/6/7/8/9/10	UDP glucuronosyltransferase 1, polypeptides A1/3/4/5/6/7/8/9/10	24.36	27.93
NM_000463	UGT1A1/4/6/8/9/10	UDP glucuronosyltransferase 1, polypeptides A1/4/6/8/9/10	15.31	17.66
NM_021027	UGT1A1/4/6/8/9/10	UDP glucuronosyltransferase 1, polypeptides A1/4/6/8/9/10	13.55	17.05
NM_001072	UGT1A1/3/4/5/6/7/8/9/10	UDP glucuronosyltransferase 1, polypeptides A1/3/4/5/6/7/8/9/10	13.21	16.88
AV691323	UGT1A1/3/4/5/6/7/8/9/10	UDP glucuronosyltransferase 1, polypeptides A1/3/4/5/6/7/8/9/10	13.05	16.82

Genes differentially expressed by at least twofold with a P-value < 0.05 including multiple testing correction were compared between MCF7 and MDA-MB-468 cells as described in Table 3.

ISSN: 1756-994X