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Figure 1 | Genome Medicine

Figure 1

From: The emerging molecular pathogenesis of neuroblastoma: implications for improved risk assessment and targeted therapy

Figure 1

A schematic overview of chromosome regions and genes known to be involved in neuroblastoma oncogenesis. This overview is not comprehensive, and only those regions and genes mentioned in the article are indicated. Gene abbreviations: ALK, anaplastic lymphoma receptor tyrosine kinase; BARD1, BRCA1 associated RING domain 1; CADM1, cell adhesion molecule 1; CDKN2A, cyclin dependent kinase inhibitor 2A; CHD5, chromodomain helicase DNA binding protein 5; KIF1B, kinesin family member 1B; MYCN, v-myc myelocytomatosis viral related oncogene, neuroblastoma derived; NME1/E2, non-metastatic cells 1, protein (NM23A) expressed in/non-metastatic cells 2, protein (NM23A) expressed in; PHOX2B, paired-like homeobox 2b; PPM1D, protein phosphatase 1D magnesium-dependent, delta isoform; RASSF1A, Ras association (RalGDS/AF-6) domain family member 1.

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Genome Medicine

ISSN: 1756-994X

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