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Figure 2 | Genome Medicine

Figure 2

From: miR-638 regulates gene expression networks associated with emphysematous lung destruction

Figure 2

MicroRNA-mRNA co-expression network for the differentially expressed microRNAs. Diamonds represent microRNAs and green circles represent target genes. Lines identify significant correlations between microRNA and gene expression patterns (FDR <0.25) with the microRNA predicted to target the gene by at least one of five sequence-based prediction algorithms. Red lines indicate positive correlations and blue lines indicate negative correlations. Red nodes indicate upregulated microRNA expression with increased emphysema severity, blue indicates downregulation. The thickness of the line correlates to the number of algorithms that predict the interaction.

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