CHD and stroke risk factors | Proteomic marker | ||||||||
---|---|---|---|---|---|---|---|---|---|
 | B2M | ORM1 | THBS1 | CFD | IGFBP1 | IGFBP2 | IGFBP4 | IGFBP6 | HPX |
Lipids | Â | Â | Â | Â | Â | Â | Â | Â | Â |
 HDL-C | -0.16 | -0.23 | -0.10 | -0.25 | 0.22 | 0.52 | -0.25 | -0.18 | -0.21 |
(-0.27, -0.05) | (-0.36, -0.09) | (-0.24, 0.06) | (-0.38, -0.11) | (0.08, 0.36) | (0.37, 0.64) | (-0.41, -0.07) | (-0.36, 0.01) | (-0.38, -0.03) | |
 LDL-C | -0.04 | 0.04 | 0.09 | -0.01 | -0.05 | -0.15 | 0.01 | 0.02 | 0.14 |
(-0.15, 0.08) | (-0.10, 0.19) | (-0.06, 0.24) | (-0.16, 0.13) | (-0.19, 0.10) | (-0.32, 0.04) | (-0.18, 0.19) | (-0.17, 0.21) | (-0.04, 0.32) | |
Inflammatory markers | Â | Â | Â | Â | Â | Â | Â | Â | Â |
 CRP | -0.04 | 0.02 | 0.12 | -0.04 | 0.05 | -0.11 | -0.02 | -0.04 | 0.13 |
(-0.15, 0.08) | (-0.12, 0.17) | (-0.03, 0.27) | (-0.18, 0.11) | (-0.10, 0.19) | (-0.28, 0.08) | (-0.21, 0.16) | (-0.23, 0.15) | (-0.06, 0.30) | |
 IL-6 | 0.09 | 0.30 | 0.09 | 0.05 | -0.11 | -0.16 | 0.30 | 0.21 | 0.23 |
(-0.03, 0.20) | (0.16, 0.43) | (-0.07, 0.24) | (-0.10, 0.20) | (-0.25, 0.04) | (-0.34, 0.03) | (0.12, 0.46) | (0.01, 0.39) | (0.05, 0.40) | |
 MMP-9 | 0.08 | 0.30 | -0.06 | 0.11 | -0.06 | -0.20 | 0.06 | 0.09 | 0.07 |
(-0.03, 0.20) | (0.16, 0.43) | (-0.21, 0.10) | (-0.03, 0.26) | (-0.20, 0.09) | (-0.37, -0.01) | (-0.12, 0.24) | (-0.11, 0.27) | (-0.11, 0.25) | |
Thrombosis and other blood markers | Â | Â | Â | Â | Â | Â | Â | Â | Â |
 Factor VIII | 0.21 | 0.14 | 0.06 | -0.02 | 0.08 | -0.11 | 0.23 | 0.19 | 0.12 |
(0.10, 0.32) | (0.00, 0.28) | (-0.10, 0.21) | (-0.16, 0.12) | (-0.07, 0.22) | (-0.29, 0.08) | (0.05, 0.39) | (0.00, 0.37) | (-0.06, 0.30) | |
 Factor 1.2 | 0.01 | -0.04 | -0.02 | 0.08 | 0.09 | 0.06 | -0.02 | 0.06 | 0.31 |
(-0.10, 0.13) | (-0.18, 0.10) | (-0.18, 0.13) | (-0.07, 0.22) | (-0.06, 0.23) | (-0.13, 0.24) | (-0.20, 0.16) | (-0.13, 0.25) | (0.14, 0.47) | |
 D-Dimer | -0.02 | 0.15 | -0.10 | 0.08 | 0.11 | -0.04 | 0.00 | 0.00 | 0.15 |
(-0.14, 0.10) | (0.00, 0.29) | (-0.26, 0.06) | (-0.07, 0.23) | (-0.04, 0.26) | (-0.23, 0.15) | (-0.19, 0.18) | (-0.19, 0.20) | (-0.04, 0.32) | |
 vWF | 0.13 | 0.22 | 0.08 | 0.36 | -0.01 | 0.15 | 0.18 | 0.09 | 0.06 |
(0.02, 0.24) | (0.07, 0.35) | (-0.22, 0.08) | (0.23, 0.48) | (-0.16, 0.13) | (-0.03, 0.33) | (0.00, 0.35) | (-0.10, 0.28) | (-0.13, 0.24) | |
 Insulin | 0.23 | -0.03 | -0.01 | 0.19 | -0.04 | 0.02 | 0.29 | 0.23 | 0.04 |
(0.12, 0.33) | (-0.17, 0.11) | (-0.16, 0.14) | (0.05, 0.32) | (-0.18, 0.11) | (-0.16, 0.21) | (0.11, 0.44) | (0.04, 0.40) | (-0.14, 0.22) | |
 Glucose | 0.03 | 0.17 | 0.02 | 0.24 | -0.44 | -0.13 | 0.29 | 0.28 | 0.26 |
(-0.08, 0.15) | (0.02, 0.31) | (-0.14, 0.17) | (0.10, 0.38) | (-0.55, -0.31) | (-0.31, 0.07) | (0.10, 0.45) | (0.08, 0.45) | (0.07, 0.43) | |
 WBC | 0.01 | 0.02 | 0.06 | 0.02 | -0.10 | -0.30 | 0.09 | 0.21 | 0.11 |
(-0.10, 0.12) | (-0.12, 0.17) | (-0.09, 0.21) | (-0.12, 0.16) | (-0.24, 0.04) | (-0.46, -0.12) | (-0.10, 0.27) | (0.02, 0.39) | (-0.08, 0.29) | |
Blood pressure | Â | Â | Â | Â | Â | Â | Â | Â | Â |
 Systolic BP | 0.08 | 0.10 | 0.17 | 0.04 | -0.03 | -0.25 | 0.00 | 0.17 | 0.14 |
(-0.04, 0.19) | (-0.04, 0.24) | (0.02, 0.32) | (-0.11, 0.18) | (-0.17, 0.12) | (-0.42, -0.07) | (-0.18, 0.18) | (-0.02, 0.35) | (-0.04, 0.31) | |
 Diastolic BP | 0.18 | 0.08 | -0.11 | 0.19 | 0.00 | -0.06 | 0.18 | 0.18 | 0.05 |
 | (0.08, 0.28) | (-0.06, 0.22) | (-0.25, 0.05) | (0.05, 0.32) | (-0.15, 0.14) | (-0.21, 0.09) | (0.03, 0.32) | (0.03, 0.33) | (-0.10, 0.19) |