Table 4 Comparison of validation results in independent test data for full-gene-set, 17-gene, and eight-gene RFRS models
From: A robust prognostic signature for hormone-positive node-negative breast cancer
Relapse-free survival | ||||||||
|---|---|---|---|---|---|---|---|---|
RFRS performance | Low risk | Intermediate risk | High risk | |||||
Model | AUC | RR | n (%) | RR | n (%) | RR | n (%) | KM ( P ) |
Full-gene-set | 0.730 | 6.9 | 78 (30.7) | 15.8 | 133 (52.4) | 26.8 | 43 (16.9) | 6.54E-06 |
17-gene | 0.715 | 7.8 | 97 (38.2) | 15.3 | 103 (40.5) | 26.8 | 54 (21.3) | 9.57E-06 |
Eight-gene | 0.690 | 9.7 | 101 (39.8) | 13.9 | 105 (41.3) | 28.3 | 48 (18.9) | 2.84E-05 |