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Figure 4 | Genome Medicine

Figure 4

From: Serum acute phase reactants hallmark healthy individuals at risk for acetaminophen-induced liver injury

Figure 4

Isoforms of haptoglobin identified as regulated in healthy volunteers prior to APAP treatment. (I) Two-dimensional gel electrophoresis showing three major isoforms of haptoglobin. (II) Results of densitometric scans of two-dimensional electrophoresis images of serum proteins regulated in DILI responders, non-responders and placebo-treated healthy volunteers prior to and after APAP treatment for 7 days. (III) Correlation of serum ALT activities and haptoglobin isoforms in DILI responders after APAP treatment for 7 days. ***P < 0.001; **P < 0.01; *P < 0.05.

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