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Figure 4 | Genome Medicine

Figure 4

From: Functional DNA quantification guides accurate next-generation sequencing mutation detection in formalin-fixed, paraffin-embedded tumor biopsies

Figure 4

Effect of FFPE DNA copy number on NGS variant calling using a commercial targeted enrichment cancer panel. A) Correlation between QFI and number of variants detected on the PGM following enrichment using the AmpliSeq Cancer Panel. (B) Samples with the lowest QFI produced a significantly larger number of variants from AmpliSeq NGS compared to those with >6% QFI (P-value 0.006).

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