Skip to main content
Figure 2 | Genome Medicine

Figure 2

From: Incremental value of rare genetic variants for the prediction of multifactorial diseases

Figure 2

Change in AUC, NRI(>0.01) and IDI per different values of the baseline AUC when common genetic variants were added to prediction baseline model. ΔAUC, change in AUC between the model with and without the common genetic variants; AUC, area under the receiver operating characteristic curve; IDI, integrated discrimination improvement; n, number of common variants added; NRI, net reclassification improvement; OR, odds ratio; p, frequency of the risk allele; AUC 1, AUC of the baseline model. Disease risk is 4%. Population size is 20,000. Results are median values from 10 simulations.

Back to article page