Figure 1

Overview detailing the differences between astrocytomas in the pediatric and adult age groups. (a) Depiction of grade distribution in adults and children highlighting that the majority of astrocytomas in adults are grade IV astrocytomas (glioblastomas), whereas the majority in the pediatric years are grade I astrocytomas (pilocytic astrocytomas). (b) Depiction of tumor localization. In adults, astrocytomas are most likely to arise in the cortex and the thalamus whereas in the pediatric years, astrocytomas are most common in the cerebellum, optic nerve and brainstem. (c) Age distribution between the four astrocytoma grades in adults and children. Grade and age data summarized from [5].